600MG Potassium Chloride Tablets Diuretics Medicines 10 *10 / Box
Potassium Chloride Tablets 600MG
Each tablet contains:
|Potassium Chloride||600 mg|
The Potassium Chloride is incorporated into a specially formulated
A 18.1 Diuretics
Lenurex-K is a diuretic which reduces the reabsorption of
electrolytes from the renal tubules, thereby increasing the
excretion of sodium, potassium and chloride ions, and consequently
of water. It also slightly increases bicarbonate excretion without
appreciable alteration of the acid-base balance or the pH of the
urine, it has a lowering effect on the blood pressure and enhances
the action of other hypotensive agents.
Cyclopenthiazide is absorbed from the gastro-intestinal tract,
distributed throughout the extracellular space and diffuses across
Diuresis occurs in about two hours, reaches a maximum in about four
hours, and lasts for about twelve hours. Tolerance does not develop
and therapeutic efficacy is maintained when it is administered over
long periods, but patients may not respond if their glomerular
filtration-rate is markedly reduced. This medicine contains
potassium chloride. It has not been proven that this dosage will
necessarily prevent a significant potassium loss or correct an
existing deficiency of potassium.
Oedema due to sodium and water retention. In patients with diabetes
insipidus, cyclopenthiazide decreased urinary volume and may
therefore be of value in the management of the disease. Essential
hypertension: preferably in combination with other antihypertensive
Patients with an established hypersensitivity towards the drug.
Severe renal and/or hepatic insufficiency.
DOSAGE AND DIRECTIONS FOR USE:
For the treatment of oedema:
The average daily dose is 2 tablets daily, preferably taken in the
In the treatment of hypertension:
The usual dose is 2 tablets daily.
1 to 2 tablets daily or every second or third day.
SIDE-EFFECTS AND SPECIAL PRECAUTIONS:
Side-effects which occur occasionally include allergies, skin
rashes epigastric pain, anorexia, gastric irritation, nausea,
vomiting, diarrhoea, constipation, photosensitivity, erythema
multiforme (the Stevens-Johnson syndrome) dizziness, headache,
weakness, inflammation of the salivary glands and paraesthesias.
Acute pancreatitis has been reported following prolonged
administration. Intestinal ulceration has also been reported.
Toxic effects such as hypochloraemic alkalosis, jaundice, and blood
dyscrasias including agranulocytosis, aplastic anaemia,
thrombocytopenia, and leucopenia have occasionally occurred.
Orthostatic hypotension which may be accentuated by alcohol,
barbiturates or narcotics has occurred. In patients with severe
congestive heart failure who are very oedematous, a low-salt
syndrome may occur, particularly with large doses. Low salt diets
should therefore be relaxed during treatment.
Cyclopenthiazide may provoke hyperglycaemia and glycosuria in
diabetic and other susceptible patients. It may cause
hyperuricaemia and precipitate attacks of gout in some patients.
The urinary excretion of calcium is reduced.
The patient should be carefully observed for signs of fluid and
electrolyte imbalance. Cyclopenthiazide should be used with caution
in patients with impaired hepatic or renal function or with
Borderline renal and/or hepatic insufficiency may be aggravated.
Blood glucose concentrations should be monitored in patients taking
Serum concentrations of protein bound iodine may increase without
signs of thyroid toxicity.
KNOWN SYMPTOMS OF OVERDOSAGE AND PARTICULARS OF ITS TREATMENT:
Hypochloraemic alkalosis and dehydration. Treatment of overdosage
CONDITIONS OF REGISTRATION:
The product may be advertised to the profession only.
Yellow sugar coated, biconvex tablet.
Packs of 28, 56, 100 and 500 tablets.
Store below 25°C.
Keep container tightly closed.
KEEP OUT OF THE REACH OF CHILDREN.