Albendazole For Oral Suspension Drugs 400mg/10ml 1 Bootle / Box
Albendazole Syrup Drugs 400mg/10ml
Each 10 ML syrup contains:400 mg of Albendazole.
Albendazole is a benzimidazole carbamate with anthelmintic and
antiprotozoal activity against intestinal and tissue parasites.
Animal studies have shown that albendazole exhibits vermicidal,
ovacidal and larvacidal activity and exerts its anthelmintic effect
by inhibiting tubulin polymerization. This causes the disruption of
the helminth metabolism, including energy depletion, which
immobilises and then kills the susceptible helminth. In man, after
oral administration, albendazole is absorbed and completely
metabolized. At a dose of 6,6 mg/kg of albendazole the plasma
concentration of its main metabolite, the sulfoxide, attains a
maximum of 0,25 to 0,30 micrograms/mL after approximately 2½ hours.
The half-life of the sulfoxide in the plasma is 8% hours. The
metabolite is essentially eliminated via the urine.
Albendazole is indicated in the treatment of single or mixed
intestinal parasites. Clinical studies have shown albeneffective in
the treatment of Ascaris lumbricoides (roundworm), Trichuris
trichiura (whipworm), Enterobius vermicularis (pinworm/threadworm), Ancylostoma duodenale and Necator americanus (hookworm), Taenia spp. (tapeworm) and Strongyloidesstercoralis.
Albendazole has been shown to be effective in the treatment of
Giardia (duodenalis or intestinalis or lamblia) infections in
Albendazole is known to be teratogenic and embryotoxic in animals.
The safety of albendazole during pregnancy has not been
established, and Albendazole should not be taken by pregnant women at any stage of their
pregnancy or by women who are likely to become pregnant, during or
shortly after the course of therapy. Albendazole is contra-indicated in patients with a known history of
hypersensitivity to albendazole or constituents.
DOSAGE AND DIRECTIONS FOR USE:
10 mL (400 mg) of Albendazole Syrup suspension as a single dose in
both adults and children over two years of age. The usual dose in
children between one and two years of age is 5 mL (200 mg) of
Albendazole Syrup suspension as a single dose. In heavy mixed
infestation involving Strongyloides or Taeniasis, a single daily
dose may be inadequate and the dose may be given for three
If the patient is not cured after three weeks, a second course of
treatment may be given. No special procedures, such as fasting or
purging, are required.
Albendazole has not been adequately studied in children under one
year of age.
Giardiasis (dose in children over 2 years of age):
A single 400 mg daily dose (10 mL suspension) for five days.
The tablets may be chewed, swallowed or crushed and they should be
taken with food.
SIDE EFFECTS AND SPECIAL PRECAUTIONS:
Gastrointestinal discomfort, diarrhoea, headache and dizziness have
Hypersensitivity reactions including rash. pruritus and urticaria
have been reported less frequently.
Praziquantel has been reported to increase the plasma levels of the
albendazole active metabolite.
Store in a cool place (below 25°C). Protect suspension from light.
KEEP OUT OF REACH OF CHILDREN.