DOXYCYCLINE 200 MG Capsules
Each capsule contains: Doxycycline hyclate equivalent to 200 mg
Doxycycline is bacteriostatic against susceptible strains of a wide
range of Gram-positive and Gram-negative bacteria.
Doxycycline is widely distributed into pleural and peritoneal
fluid, saliva, semen and prostatic fluid. It passes the placental
barrier readily and is also present in the milk of lactating
patients. It is concentrated by the liver and excreted, by way of
the bile, into the intestine from which it is partially reabsorbed.
Conventional doses of doxycycline are not excreted in the urine to
the same extent as other tetracyclines and it does not accumulate
significantly in the blood of patients with renal failure.
Extrarenal infections in individuals may be treated with
doxycycline when indicated. Doxycycline is excreted in the faeces,
largely as an inactive conjugate or chelate.
For the treatment of Brucellosis, trachoma, urinary tract
infections, sensitive gonococcal infections.
Pregnancy and lactation and in young children. Sensitivity to any
tetracycline. As preparations containing iron, aluminium, calcium
or magnesium decrease the absorption of doxycycline, do not give to
patients receiving antacid therapy, milk or calcium containing
foods. Potentially hepatotoxic medicine should not be given with
Use with care in liver function impairment. Symptoms of myasthenia
gravis may be aggravated. Photosensitivity may occur.
DOSAGE AND DIRECTIONS FOR USE:
Doxycycline should be taken one hour before meals or two hours
Adults: one capsule every 24 hours.
Absorption of CYCLIDOX EC is diminished by milk, alkalis, aluminium
hydroxide and other di- and trivalent cations such as calcium, iron
and magnesium if they are given concomitantly. Doses of
anticoagulants may need to be reduced if given concomitantly with
CYCLIDOX EC. Doxycycline may decrease the efficacy of oral
contraceptives. Penicillin should not be given concomitantly with
CYCLIDOX EC as antagonism in action may occur.
Store below 25°C and protect from light.
KEEP OUT OF REACH OF CHILDREN.